Understanding Radiobiological Drivers Beyond Absorbed Dose to Strengthen RLT Candidate Selection
11:30 am - Thursday 25th February 2027
- Interrogate cellular uptake and target-specific biology to understand how biological characteristics influence therapeutic response beyond absorbed dose alone
- Leverage knockout and knock-in models alongside in vitro and in vivo validation to establish target-specific effects and strengthen confidence in the underlying biology
- Integrate imaging and therapy studies throughout preclinical development to connect biological response with candidate performance and inform progression towards the clinic
