Building Preclinical Models that Better Recapitulate Human RLT Biology to Improve Prediction of Clinical Performance – Reserved for AstraZeneca
9:30 am - Thursday 25th February 2027
- Selecting models that reproduce clinically relevant target expression, heterogeneity & tumor biology to generate more representative preclinical data
- Identifying where conventional xenografts misrepresent human disease to avoid overestimating candidate performance
- Defining the characteristics required of a predictive model to support higherconfidence candidate progression