Felix Gremse
Seminars
Wednesday 25th February 2026
Pivot or Proceed? How AI-Assisted Quantitative Imaging Accelerates Target Validation & Candidate Selection
8:30 am
- Regulatory guidance now requires consistency between preclinical and clinical assessment of biodistribution, target engagement, and dosimetry, making quantitative imaging of PDX models a necessary translational bridge
- Standardized imaging protocols and quality-control phantoms establish a scalable, quantitative foundation for early target validation across sites
- AI-driven analysis extracts reproducible, high-throughput evidence from imaging data to accelerate go/no-go candidate decisions
